Headspace Gas Chromatography
Headspace gas chromatography is most suited to the analysis of the very light volatiles in samples that can be efficiently partitioned into the headspace gas volume from the liquid or solid matrix sample. Higher boiling volatiles and semi-volatiles are not detectable with this technique due to their low partition in the gas headspace volume. Partitioning is covered in more detail later in this article.
Headspace gas analysis also lends itself to automation for quality control or sample screening. This is made possible by modern instrumentation, through which highly reproducible samples can be prepared in an efficient and accurate manner.
Complex sample matrices, which may be difficult to analyse directly or would otherwise require sample extraction or preparation, are ideal candidates for headspace since they can be placed directly in a vial with little or no preparation. This saves both time and money.
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Ms. Shradhdha Nakum
Experience : 3 years